Hyaluronic Acid Bulk, Sodium Hyaluronate Bulk

SODIUM HYALURONATE (Hyaluronic Acid), Powder, Cosmetic Grade and Nutritional Grade SPECIFICATION NO. 4917-55
Description:	Fine white powder, with no odor
Chemical Formula:	C₁₄H₂₀NNaO₁₁_n	FW 56.11
CAS Number:	9067-32-7
DOT Information:	Non-Regulated
Specification:	Infrared Spectrum	To Pass Test
	pH of a 0.5% Aqueous Solution	6–8
	Water Content (KF)	10%
	Residue on Ignition	7–10%
	Protein Content	0.1%
	Uronic Acid Content (dry basis)	45.0–48.4%
	Sodium Hyaluronate (dry basis)	93–100%
	Total Aerobic Plate Count	100 CFU/g
	Nonconforming Organisms	None Recovered
Other Parameters:	Solubility @ 0.5% W/V in Freshly Distilled H₂O	Complete
	Complete Appearance of a 0.5% Aqueous Solution (clear, slightly opalescent, colorless, viscous liquid)	To Pass Test
	Total Nitrogen (dry basis)	3.0–3.6%
	Sodium Glucuronate (dry basis)	51.2–53.9%
	Molecular Weight Range	5.0 KDa to 3.0 MDa
	Preservative	None
Packing:	Poly Containers with Tamper-Proof Safety Seals, 500 g.
Application:	Cosmetic, Nutritional

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SODIUM HYALURONATE (Hyaluronic Acid), Powder, Pharmaceutical Grade (Ph. Eur. 3, Supp. 2000:1472) SPECIFICATION NO. 4917-13P-2
Description:	Fine white powder, with no odor Meets the requirements of the European Pharmacopeia 3, Supp. 2000:1472
Chemical Formula:	C₁₄H₂₀NNaO₁₁_n
CAS Number:	9067-32-7
DOT Information:	Nonregulated
Specification:
	Identification: a) Infrared Spectrum b) Sodium	To Pass Test To Pass Test
	Appearance of Solution S	Clear
	Absorbance of Solution (A₆₀₀ nm)	0.010
	pH of a 0.5% aqueous solution	5–8.5
	Intrinsic Viscosity @ 25°C	2–3.5 m³/kg
	Molecular Weight Range	0.1 – 2.0 x 10⁶ Da
	Neucleic Acid (A₂₆₀ nm of S solution)	0.2
	Protein Content	0.1%
	Chloride	0.5%
	Iron	80 ppm
	Loss on Drying	10%
	Total Microbial Count	100 CFU/g
	Microbial Endotoxins	0.05 I.U./mg
	Uronic Acid Content (dry basis)	45.9-50.8%
	Sodium Hyaluronate (dry basis)	95.0-105.0%
	Kinematic Viscosity	1.95 cSt
Packing:	PE Container with Tamper-Proof Safety Seal, 100 g. or 500 g.
Applications:	Pharmaceutical, Veterinary

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SODIUM HYALURONATE (Hyaluronic Acid) 1-2 % Aqueous Solution SPECIFICATION NO. 4918-55
Description:	1-2% (nominal) aqueous solution with preservative (actual concentration specified by customer)
Chemical Formula:	C₁₄H₂₀NNaO₁₁_n
CAS Number:	9067-32-7
DOT Information:	Nonregulated
Actual Lot Analysis:
	Assay	10.0–20.0 g/L
	Molecular Weight Range	1.5–1.8 x 10⁶ Da
	Viscosity	2.8 cSt
	Protein	10 mg/L
	Optical Density (@660 nm)	0.01
	pH	6–8
	Microbial Count	100 CFU/ml
	Preservative (Phenonip)	3.0 g/L
Packing:	Poly Containers	5 L, 20 L
Application:	Cosmetic

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